Epilepsy is a brain disease that makes nerve cells act strangely, leading to seizures. Seizures are like unexpected bursts of electricity in the brain that can change how you feel, act, think, and move. Even though epilepsy can’t be fully fixed, there are many ways to help. Most people with epilepsy, about 70%, can control it using medicines.
Epilepsy is a chronic condition causing repeated seizures due to abnormal electrical signals from damaged brain cells. Seizures happen when there’s an uncontrolled burst of electrical activity in the brain, leading to changes in awareness, muscle control (twitching or jerking), sensations, emotions, and behavior. Another term for epilepsy is a seizure disorder.
In the United States, approximately 3.4 million individuals live with epilepsy, with 3 million being adults and 470,000 children. Annually, there are 150,000 new cases of epilepsy in the U.S. On a global scale, about 65 million people grapple with epilepsy.
Your brain’s intricate network of cells constantly communicates with and receives messages from various parts of your body through a continuous electrical impulse. Epilepsy disrupts this normal electrical pattern, causing unpredictable bursts of energy, akin to an erratic lightning storm, between cells in one or more brain areas. This electrical disturbance leads to alterations in awareness (including loss of consciousness), sensations, emotions, and muscle movements.
Epilepsy primarily manifests through recurring seizures, with specific symptoms varying based on the seizure type. Common signs include:
Individuals with epilepsy usually experience consistent symptoms with each seizure.
Determining the cause of seizures is often challenging, with up to 70% of cases having unknown origins. Recognized causes include:
Epilepsy management involves various approaches, including anti-seizure medications, specialized diets, and, in severe cases, surgical interventions.
Anti-Seizure Medications:
These medications aim to control seizures, with success rates ranging from 60% to 70%. Treatment is personalized, considering factors such as seizure type, past medication responses, other medical conditions, potential interactions, side effects, age, general health, and cost. More than 20 FDA-approved anti-seizure medications offer a diverse range of options. If medication trials prove ineffective, alternative treatments may be explored.
Diet Therapy:
For individuals, especially children, where medications show limited effectiveness or are not viable due to other considerations, diet therapy becomes an option. The ketogenic diet and modified Atkins diet, both emphasizing high fat, moderate protein, and low carbohydrates, are commonly recommended. Additionally, low glycemic index diets may prove beneficial for some.
Surgery and Devices:
In cases where seizures persist despite medication trials and they significantly impact daily life, surgery may be considered. Epilepsy surgery, conducted at specialized centers, becomes an option when multiple medication trials fail. Surgical approaches include resection (removing abnormal tissue), disconnection (cutting fiber bundles connecting brain areas), stereotactic radiosurgery (targeted destruction of abnormal brain tissue), or implantation of neuromodulation devices. These devices emit electrical impulses to the brain, gradually reducing seizures.
Comprehensive Evaluation:
Before opting for surgery or advanced treatments, a thorough evaluation at an epilepsy center is crucial. This assessment determines candidacy and ensures a safe and effective course of action, particularly if conventional anti-seizure medications prove insufficient.
In epilepsy treatment, the goal is to find the most suitable approach tailored to individual needs, striving to enhance overall quality of life.
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